ATP6V0D2

Across TCGA patient cohorts, ATP6V0D2 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6V0D2-associated genes across cancer lineages are PDCD4, INPP4B, and MSH2. Each is linked with ATP6V0D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V0D2-to-partner and partner-to-ATP6V0D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by ATP6V0D2-low versus ATP6V0D2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0D2→partner) and Y-score (partner→ATP6V0D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.514	-1.584	.005	.036	3	2
UCEC	INPP4B →	-0.309	-3.459	.014	.005	3	1
UCEC	MSH2 →	-0.213	-2.674	.018	.005	3	1
UCEC	PCNA →	+0.175	+2.459	.039	.019	3	1
UCEC	Rad50 →	-0.236	-2.502	.013	.002	3	1
UCEC	Annexin-1 →	+0.437	+2.999	.034	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

PDCD4 by ATP6V0D2 expression — UCEC

Explore this box plot interactively →