ATP6V0D2

Across TCGA cell cohorts, ATP6V0D2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP6V0D2-associated genes across cancer lineages are REG1B, USP17L7, and OR6B3. Each is linked with ATP6V0D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V0D2-to-partner and partner-to-ATP6V0D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REG1B grouped by ATP6V0D2-low versus ATP6V0D2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0D2→partner) and Y-score (partner→ATP6V0D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	REG1B →	+2.025	+3.196	.001	.007	3	1
LARGE_INTESTINE	USP17L7 →	+0.089	+3.691	<.001	.009	3	1
LUNG_SCLC	OR6B3 →	+0.031	+4.269	<.001	.005	3	1
LUNG_SCLC	TBC1D3H →	+0.325	+4.269	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

REG1B by ATP6V0D2 expression — LARGE_INTESTINE

Explore this box plot interactively →