Across TCGA patient cohorts, ATP6V0C RNA expression is significantly associated with the go_rna of many other GO terms, with 7,158 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible ATP6V0C-associated GO terms across cancer lineages are Endosomal lumen acidification, Positive regulation of exosomal secretion, and Regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide. Each is linked with ATP6V0C in more than 21 cancer types. Because this analysis shows association rather than direction, both ATP6V0C-to-partner and partner-to-ATP6V0C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0C→partner) and Y-score (partner→ATP6V0C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Endosomal lumen acidification →	+0.072	+0.951	.008	.007	1	22
DLBC	Positive regulation of exosomal secretion →	+0.095	+1.010	<.001	.004	2	20
SCLC	Regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide →	+0.081	+0.729	.001	<.001	1	21
DLBC	Maintenance of protein location in mitochondrion →	+0.084	+1.039	.003	.002	2	18
CHOL	Synaptic vesicle maturation →	+0.088	+0.800	<.001	<.001	3	17
CHOL	Synaptic vesicle lumen acidification →	+0.080	+0.625	.005	.006	1	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,158 associations by consensus.

Exploration

ATP6V0C survival (RNA) · tumor vs normal (RNA) · all ATP6V0C data types