Across TCGA cell cohorts, ATP6V0C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,429 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATP6V0C-associated GO terms across cancer lineages are Negative regulation of autophagosome maturation, Multi-pass transmembrane protein insertion into ER membrane, and Transcription pausing by RNA polymerase II. Each is linked with ATP6V0C in more than 12 cancer types. Because this analysis shows association rather than direction, both ATP6V0C-to-partner and partner-to-ATP6V0C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0C→partner) and Y-score (partner→ATP6V0C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of autophagosome maturation →	+0.111	+0.966	.001	.002	3	13
BONE	Multi-pass transmembrane protein insertion into ER membrane →	+0.126	+0.961	<.001	<.001	3	13
BONE	Transcription pausing by RNA polymerase II →	+0.138	+0.761	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of ATP metabolic process →	+0.064	+0.893	.006	.002	3	12
BLOOD_Myeloma	Vacuolar acidification →	+0.135	+1.216	<.001	.002	2	13
UPPER_AERODIGESTIVE_TRACT	Vesicle uncoating →	+0.162	+1.111	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,429 associations by consensus.

Exploration

ATP6V0C survival (RNA) · tumor vs normal (RNA) · all ATP6V0C data types