Across TCGA patient cohorts, ATP6V0A2 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6V0A2-associated genes across cancer lineages are MEK1, Tuberin, and eIF4E. Each is linked with ATP6V0A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V0A2-to-partner and partner-to-ATP6V0A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0A2→partner) and Y-score (partner→ATP6V0A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.403	+2.700	.005	.006	3	2
UCEC	Tuberin →	+0.283	+2.000	.007	.010	3	2
UCEC	eIF4E →	+0.190	+3.013	.021	.018	3	1
UCEC	ERK2 →	+0.219	+2.700	.003	.006	3	1
UCEC	JNK_pT183_Y185 →	-0.188	-2.584	.004	.010	3	1
UCEC	JNK2 →	+0.210	+3.026	.007	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

ATP6V0A2 survival (RNA) · tumor vs normal (RNA) · all ATP6V0A2 data types