Across TCGA cell cohorts, ATP6V0A2 mutation is significantly associated with the RNA expression of many other genes, with 217 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP6V0A2-associated genes across cancer lineages are EN1, RASL10A, and APOL4. Each is linked with ATP6V0A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V0A2-to-partner and partner-to-ATP6V0A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0A2→partner) and Y-score (partner→ATP6V0A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	EN1 →	+0.644	+4.765	<.001	<.001	3	2
LARGE_INTESTINE	RASL10A →	+0.426	+3.295	<.001	.003	3	1
LARGE_INTESTINE	APOL4 →	+0.830	+2.392	<.001	.009	3	1
LARGE_INTESTINE	SAMD15 →	+0.527	+3.299	<.001	.004	3	1
LARGE_INTESTINE	FZD3 →	+0.794	+3.212	.002	.006	3	1
LARGE_INTESTINE	SNX16 →	+0.573	+3.212	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 217 associations by consensus.

Exploration

ATP6V0A2 survival (RNA) · tumor vs normal (RNA) · all ATP6V0A2 data types