ATP6AP2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP6AP2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,128 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATP6AP2-associated genes across cancer lineages are SYNE1, PGM5, and FBLN5. Each is linked with ATP6AP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ATP6AP2-to-partner and partner-to-ATP6AP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP6AP2 versus SYNE1 in UCEC, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6AP2→partner) and Y-score (partner→ATP6AP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSYNE1 →-0.618-0.276.006.00936
BRCAPGM5 →-0.838-0.366.001.00236
BRCAFBLN5 →-1.333-0.430<.001<.00135
BRCACHRDL1 →-1.940-0.415<.001<.00135
BRCAADH1B →-1.941-0.327<.001.00235
BRCAGALNT16 →-0.825-0.304.001.00334
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,128 associations by consensus.

ATP6AP2 vs SYNE1 — UCEC

Per-sample scatter of ATP6AP2 vs SYNE1 in UCEC (Pearson r = -0.29).

Explore this scatter interactively →

Exploration