ATP6AP2

Across TCGA patient cohorts, ATP6AP2 mutation is significantly associated with the RNA expression of many other genes, with 3,869 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6AP2-associated genes across cancer lineages are RN7SL134P, RNA5SP412, and RNU6-275P. Each is linked with ATP6AP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP6AP2-to-partner and partner-to-ATP6AP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by ATP6AP2-low versus ATP6AP2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6AP2→partner) and Y-score (partner→ATP6AP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL134P →	+0.175	+4.874	<.001	.002	3	3
UCEC	RNA5SP412 →	+0.615	+2.382	<.001	<.001	3	2
CESC	RNU6-275P →	+0.340	+5.569	<.001	.002	3	2
LUSC	MIR1272 →	+0.522	+5.211	<.001	.007	3	2
READ	OR6K5P →	+0.057	+6.257	<.001	.001	3	2
BLCA	RNU7-173P →	+0.674	+4.899	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,869 associations by consensus.

RN7SL134P by ATP6AP2 expression — CESC

Explore this box plot interactively →