ATP6AP1

Across TCGA pan-cancer cohorts, ATP6AP1 mass-spec protein differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of ATP6AP1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ATP6AP1 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types ATP6AP1 is over-expressed in tumor.

COAD, HNSC, and LUAD are the cancer types where ATP6AP1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP6AP1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	+0.491	<.001	12	view →
HNSC	All	IV	+0.295	<.001	12	view →
LUAD	All	III,IV	+0.359	<.001	9	view →
LSCC	Male	II,III,IV	+0.239	<.001	7	view →
PDAC	Female	II,III,IV	+0.275	.041	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

ATP6AP1–COAD

Open the COAD breakdown →