ATP6AP1

Across TCGA patient cohorts, ATP6AP1 mutation is significantly associated with the RNA expression of many other genes, with 2,191 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6AP1-associated genes across cancer lineages are RNU6-993P, MIR4686, and RNU6-715P. Each is linked with ATP6AP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6AP1-to-partner and partner-to-ATP6AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-993P grouped by ATP6AP1-low versus ATP6AP1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6AP1→partner) and Y-score (partner→ATP6AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-993P →	+0.298	+4.970	<.001	.005	3	2
SKCM	MIR4686 →	+0.371	+5.328	<.001	.003	3	2
BLCA	RNU6-715P →	+0.295	+6.040	<.001	.001	3	2
STAD	RNU6-258P →	+0.712	+4.184	<.001	.009	3	2
STAD	LINC00428 →	+0.462	+4.520	<.001	.005	3	2
STAD	RNU7-144P →	+0.536	+6.383	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,191 associations by consensus.

RNU6-993P by ATP6AP1 expression — SKCM

Explore this box plot interactively →