ATP5PFP1

Across TCGA patient cohorts, ATP5PFP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,146 significant associations in total. OV shows the largest number of these associations.

The most reproducible ATP5PFP1-associated GO terms across cancer lineages are [2Fe-2S] cluster assembly, rRNA pseudouridine synthesis, and Proton transmembrane transport. Each is linked with ATP5PFP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ATP5PFP1-to-partner and partner-to-ATP5PFP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, [2Fe-2S] cluster assembly grouped by ATP5PFP1-low versus ATP5PFP1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5PFP1→partner) and Y-score (partner→ATP5PFP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	[2Fe-2S] cluster assembly →	+0.053	+0.259	<.001	<.001	3	8
READ	rRNA pseudouridine synthesis →	+0.031	+0.787	<.001	<.001	3	7
READ	Proton transmembrane transport →	+0.019	+0.650	<.001	<.001	3	7
ESCA	Proton motive force-driven ATP synthesis →	+0.043	+0.162	.002	.003	2	7
READ	tRNA thio-modification →	+0.055	+0.695	<.001	<.001	3	6
COAD	DNA protection →	+0.032	+0.439	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,146 associations by consensus.

[2Fe-2S] cluster assembly by ATP5PFP1 expression — ESCA

Explore this box plot interactively →