ATP5PDP4

Across TCGA pan-cancer cohorts, ATP5PDP4 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of ATP5PDP4’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ATP5PDP4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATP5PDP4 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

COAD, THCA, and HNSC are the cancer types where ATP5PDP4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP5PDP4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.451	.009	6	view →
THCA	All	All	−0.347	.001	4	view →
HNSC	All	All	+0.308	.005	3	view →
CHOL	All	All	+0.927	.028	1	view →
KICH	Female	All	−0.467	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

ATP5PDP4–COAD

Open the COAD breakdown →