ATP5PB

Across TCGA patient cohorts, ATP5PB protein abundance is significantly associated with the RNA expression of many other genes, with 12,648 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATP5PB-associated genes across cancer lineages are FBN1, DDR2, and ANTXR2. Each is linked with ATP5PB in more than 6 cancer types. Because this analysis shows association rather than direction, both ATP5PB-to-partner and partner-to-ATP5PB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP5PB versus FBN1 in OV, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5PB→partner) and Y-score (partner→ATP5PB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FBN1 →	-1.207	-0.333	.008	.005	3	7
OV	DDR2 →	-1.030	-0.269	<.001	<.001	3	6
OV	ANTXR2 →	-0.847	-0.301	<.001	.003	3	6
BRCA	CAVIN1 →	-0.987	-0.380	<.001	<.001	3	6
BRCA	KIRREL1 →	-0.989	-0.479	<.001	<.001	3	6
COAD	PTPN12 →	-0.565	-0.231	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,648 associations by consensus.

ATP5PB vs FBN1 — OV

Explore this scatter interactively →