ATP5MPL

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP5MPL protein abundance is significantly associated with the RNA expression of many other genes, with 9,356 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ATP5MPL-associated genes across cancer lineages are CALU, KANK2, and MRC1. Each is linked with ATP5MPL in more than 3 cancer types. Because this analysis shows association rather than direction, both ATP5MPL-to-partner and partner-to-ATP5MPL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP5MPL versus CALU in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5MPL→partner) and Y-score (partner→ATP5MPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACALU →-0.501-0.756.005<.00134
OVKANK2 →-0.730-0.573.009.00434
GBMMRC1 →-1.308-0.356.002<.00134
UCECAPBB1 →-0.722-0.401.001.00934
LSCCMAML2 →-0.559-0.401.005.00134
BRCAPRKCA →-0.823-0.868<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,356 associations by consensus.

ATP5MPL vs CALU — BRCA

Per-sample scatter of ATP5MPL vs CALU in BRCA (Pearson r = -0.34).

Explore this scatter interactively →

Exploration