ATP5MGP8

Across TCGA pan-cancer cohorts, ATP5MGP8 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of ATP5MGP8’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where ATP5MGP8 RNA is repressed in tumor relative to normal tissue. In most cancer types ATP5MGP8 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, LIHC, and BRCA are the cancer types where ATP5MGP8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP5MGP8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.148	<.001	5	view →
LIHC	All	All	+0.033	.015	4	view →
BRCA	All	III,IV	−0.264	.005	2	view →
UCEC	All	All	−0.213	.017	2	view →
PRAD	All	All	+0.163	.032	2	view →
CHOL	All	All	+0.226	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

ATP5MGP8–THCA

Open the THCA breakdown →