Across TCGA pan-cancer cohorts, ATP5MGL Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ATP5MGL data layer compared with 24 for mass-spec protein.
The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher ATP5MGL Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ATP5MGL expression acts as an unfavorable survival marker.
CESC are the cancer types where ATP5MGL Mutation most reproducibly stratifies survival.