ATP5MG

Across TCGA pan-cancer cohorts, ATP5MG mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ATP5MG data layer compared with 22 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ATP5MG mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ATP5MG expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

COAD, HNSC, and PDAC are the cancer types where ATP5MG mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →
HNSC	OS	Median	All	0.484	1.000	.038	6	view →
PDAC	DFS	Median	III,IV	0.506	0.154	.016	6	view →
LUAD	DFS	Median	All	0.499	0.754	.017	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ATP5MG–COAD (DFS)

Open the COAD breakdown →