ATP5MG

Across TCGA patient cohorts, ATP5MG mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP5MG-associated genes across cancer lineages are NDUFA3P3, SAP18P1, and SYPL1P1. Each is linked with ATP5MG in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP5MG-to-partner and partner-to-ATP5MG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDUFA3P3 grouped by ATP5MG-low versus ATP5MG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5MG→partner) and Y-score (partner→ATP5MG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NDUFA3P3 →	+0.426	+5.003	<.001	.002	3	2
UCEC	SAP18P1 →	+0.170	+4.551	<.001	.009	3	2
CESC	SYPL1P1 →	+0.048	+5.539	.007	.004	3	1
CESC	RPL23AP94 →	+0.115	+5.201	.008	.007	3	1
CESC	LINC02213 →	+0.054	+5.010	.001	.009	3	1
CESC	MTND4P29 →	+0.029	+5.103	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

NDUFA3P3 by ATP5MG expression — UCEC

Explore this box plot interactively →