ATP5MFP5

Across TCGA pan-cancer cohorts, ATP5MFP5 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated ATP5MFP5 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher ATP5MFP5 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ATP5MFP5 expression acts as an unfavorable survival marker, although some lineages such as LUSC and PCPG show a favorable association.

LUSC, KICH, and ACC are the cancer types where ATP5MFP5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	All	0.552	0.339	.001	64	view →
KICH	OS	Median	II,III,IV	0.461	0.948	.004	49	view →
ACC	OS	Median	II,III,IV	0.763	0.941	.001	44	view →
KIRC	OS	Quartile	All	0.547	0.696	.005	31	view →
LGG	DFS	Tertile	All	0.650	0.792	<.001	25	view →
THCA	DFS	Quartile	All	0.632	0.925	.009	16	view →
PAAD	OS	Quartile	All	0.544	0.717	.016	14	view →
COAD	OS	Quartile	IV	0.283	0.769	.004	12	view →
KIRP	OS	Median	All	0.595	0.793	.012	11	view →
CHOL	DFS	Quartile	III,IV	0.031	0.539	.008	9	view →
ESCA	DFS	Median	All	0.219	0.401	.005	9	view →
DLBC	DFS	Median	IV	0.128	1.000	.017	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

ATP5MFP5–LUSC (OS)

Open the LUSC breakdown →