ATP5MFP4

Across TCGA pan-cancer cohorts, ATP5MFP4 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ATP5MFP4 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher ATP5MFP4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ATP5MFP4 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

CESC, KIRC, and UVM are the cancer types where ATP5MFP4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Median	III,IV	0.558	0.846	<.001	110	view →
KIRC	OS	Median	All	0.564	0.691	<.001	107	view →
UVM	DFS	Quartile	II,III,IV	0.346	0.654	.001	64	view →
HNSC	OS	Median	All	0.820	0.717	.004	45	view →
READ	DFS	Median	III,IV	0.202	0.513	.006	38	view →
LUAD	DFS	Median	III,IV	0.692	0.333	.001	27	view →
MESO	OS	Tertile	All	0.159	0.649	.002	24	view →
LGG	DFS	Quartile	All	0.710	0.888	.003	20	view →
UCS	DFS	Tertile	All	0.116	0.421	.024	16	view →
ACC	DFS	Tertile	III,IV	0.697	0.204	.001	12	view →
LIHC	OS	Median	III,IV	0.248	0.460	.010	10	view →
DLBC	DFS	Median	All	1.000	0.364	.008	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ATP5MFP4–CESC (DFS)

Open the CESC breakdown →