ATP5MF

Across TCGA patient cohorts, ATP5MF mutation is significantly associated with the RNA expression of many other genes, with 84 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP5MF-associated genes across cancer lineages are TRIAP1P1, RN7SL155P, and MIR4672. Each is linked with ATP5MF in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP5MF-to-partner and partner-to-ATP5MF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIAP1P1 grouped by ATP5MF-low versus ATP5MF-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5MF→partner) and Y-score (partner→ATP5MF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRIAP1P1 →	+0.436	+4.771	<.001	.006	3	2
UCEC	RN7SL155P →	+0.277	+4.484	.004	.009	3	1
UCEC	MIR4672 →	+0.898	+4.211	<.001	.009	3	1
UCEC	RN7SL147P →	+0.420	+4.398	<.001	.006	3	1
UCEC	RN7SL468P →	+0.258	+5.123	<.001	.004	3	1
UCEC	MIR3690 →	+0.946	+4.809	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 84 associations by consensus.

TRIAP1P1 by ATP5MF expression — UCEC

Explore this box plot interactively →