ATP5MF-PTCD1

Across TCGA patient cohorts, ATP5MF-PTCD1 mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ATP5MF-PTCD1-associated genes across cancer lineages are ATP6V1E1P2, RN7SL607P, and RN7SKP181. Each is linked with ATP5MF-PTCD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP5MF-PTCD1-to-partner and partner-to-ATP5MF-PTCD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP6V1E1P2 grouped by ATP5MF-PTCD1-low versus ATP5MF-PTCD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5MF-PTCD1→partner) and Y-score (partner→ATP5MF-PTCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP6V1E1P2 →	+0.290	+4.661	.002	.004	3	2
UCEC	RN7SL607P →	+0.362	+4.233	.008	.009	3	2
LUSC	RN7SKP181 →	+0.136	+7.924	.006	.008	3	1
LUSC	RNU6-1014P →	+0.366	+7.924	<.001	.008	3	1
SKCM	MED15P7 →	+0.045	+4.867	<.001	.005	3	1
SKCM	LINC01496 →	+0.156	+4.771	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

ATP6V1E1P2 by ATP5MF-PTCD1 expression — UCEC

Explore this box plot interactively →