ATP5MF-PTCD1

Across TCGA cell cohorts, ATP5MF-PTCD1 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ATP5MF-PTCD1-associated genes across cancer lineages are H1-8, BMP5, and NRK. Each is linked with ATP5MF-PTCD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP5MF-PTCD1-to-partner and partner-to-ATP5MF-PTCD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H1-8 grouped by ATP5MF-PTCD1-low versus ATP5MF-PTCD1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5MF-PTCD1→partner) and Y-score (partner→ATP5MF-PTCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	H1-8 →	+0.022	+5.357	<.001	.001	3	1
SKIN	BMP5 →	+0.282	+3.906	.002	.001	3	1
SKIN	NRK →	+1.065	+4.000	<.001	.004	3	1
SKIN	SAG →	+0.115	+3.115	<.001	.004	3	1
SKIN	IZUMO2 →	+0.090	+3.514	<.001	.001	3	1
SKIN	CFAP221 →	+0.262	+4.029	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

H1-8 by ATP5MF-PTCD1 expression — CNS

Explore this box plot interactively →