ATP5MC2

Across TCGA patient cohorts, ATP5MC2 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP5MC2-associated genes across cancer lineages are Mesangial cells, Sebocytes, and Th2 cells. Each is linked with ATP5MC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP5MC2-to-partner and partner-to-ATP5MC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesangial cells grouped by ATP5MC2-low versus ATP5MC2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5MC2→partner) and Y-score (partner→ATP5MC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Mesangial cells →	+0.015	+4.875	<.001	.002	3	1
UCEC	Sebocytes →	-0.030	-2.967	.020	.036	3	1
UCEC	Th2 cells →	+0.218	+3.321	.021	.010	3	1
UCEC	Osteoblast →	+0.061	+2.191	.010	.035	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Mesangial cells by ATP5MC2 expression — SKCM

Explore this box plot interactively →