ATP5MC2

Across TCGA cell cohorts, ATP5MC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,968 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ATP5MC2-associated GO terms across cancer lineages are Cell junction assembly, Cell-substrate junction assembly, and Positive regulation of intracellular protein transport. Each is linked with ATP5MC2 in more than 10 cancer types. Because this analysis shows association rather than direction, both ATP5MC2-to-partner and partner-to-ATP5MC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell junction assembly grouped by ATP5MC2-low versus ATP5MC2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5MC2→partner) and Y-score (partner→ATP5MC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cell junction assembly →	-0.067	-0.970	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Cell-substrate junction assembly →	-0.156	-0.598	.003	.002	3	11
BONE	Positive regulation of intracellular protein transport →	-0.079	-0.987	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Protein linear polyubiquitination →	-0.140	-1.105	.005	<.001	3	10
BONE	Cell-matrix adhesion →	-0.129	-0.684	<.001	<.001	3	10
BONE	Hemidesmosome assembly →	-0.410	-0.812	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,968 associations by consensus.

Cell junction assembly by ATP5MC2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →