Across TCGA pan-cancer cohorts, ATP5MC1P4 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of ATP5MC1P4’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ATP5MC1P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATP5MC1P4 is over-expressed in tumor.
HNSC, BLCA, and KIRC are the cancer types where ATP5MC1P4 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP5MC1P4 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.