ATP5MC1P3

Across TCGA pan-cancer cohorts, ATP5MC1P3 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated ATP5MC1P3 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ATP5MC1P3 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ATP5MC1P3 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BLCA show a favorable association.

HNSC, COAD, and BLCA are the cancer types where ATP5MC1P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	II,III,IV	0.779	0.271	<.001	78	view →
COAD	OS	Tertile	All	0.488	0.680	<.001	60	view →
BLCA	OS	Tertile	II,III,IV	0.829	0.681	.004	48	view →
KIRP	DFS	Median	All	0.905	0.627	.010	48	view →
ESCA	DFS	Median	All	0.292	0.429	.021	15	view →
BRCA	OS	Quartile	III,IV	0.909	0.801	.020	14	view →
PRAD	DFS	Quartile	All	0.773	0.905	.010	14	view →
KIRC	DFS	Tertile	II,III,IV	0.397	0.592	.010	13	view →
LUSC	DFS	Tertile	III,IV	1.000	0.387	.026	12	view →
MESO	OS	Tertile	All	0.465	0.280	.018	10	view →
THCA	DFS	Median	All	0.891	0.719	.027	7	view →
STAD	DFS	Median	IV	0.152	0.503	.006	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

ATP5MC1P3–HNSC (DFS)

Open the HNSC breakdown →