ATP5MC1P1

Across TCGA pan-cancer cohorts, ATP5MC1P1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of ATP5MC1P1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where ATP5MC1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATP5MC1P1 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

BRCA, HNSC, and LUSC are the cancer types where ATP5MC1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP5MC1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	+0.148	<.001	4	view →
HNSC	All	All	+0.044	.018	4	view →
LUSC	All	All	+0.079	.002	3	view →
COAD	Male	IV	−0.114	.044	2	view →
KICH	All	All	−0.063	.036	1	view →
THCA	All	All	−0.033	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

ATP5MC1P1–BRCA

Open the BRCA breakdown →