ATP5IF1

Across TCGA pan-cancer cohorts, ATP5IF1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ATP5IF1 data layer compared with 27 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ATP5IF1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ATP5IF1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and COAD show a favorable association.

PDAC, COAD, and LUAD are the cancer types where ATP5IF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	II,III,IV	0.977	0.690	<.001	92	view →
COAD	DFS	Tertile	II,III,IV	1.000	0.856	.037	24	view →
LUAD	DFS	Tertile	II,III,IV	0.734	0.176	.007	17	view →
UCEC	DFS	Quartile	All	0.960	0.818	.032	2	view →
HNSC	DFS	Tertile	II,III,IV	0.897	0.990	.030	2	view →
LSCC	DFS	Quartile	III,IV	0.389	0.894	.028	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ATP5IF1–PDAC (OS)

Open the PDAC breakdown →