ATP5IF1

Across TCGA patient cohorts, ATP5IF1 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP5IF1-associated genes across cancer lineages are SNX3P1X, OR8S21P, and RNU6-755P. Each is linked with ATP5IF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP5IF1-to-partner and partner-to-ATP5IF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNX3P1X grouped by ATP5IF1-low versus ATP5IF1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5IF1→partner) and Y-score (partner→ATP5IF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNX3P1X →	+0.719	+5.771	<.001	.003	3	2
UCEC	OR8S21P →	+0.558	+5.484	<.001	.005	3	1
SKCM	RNU6-755P →	+0.288	+7.816	<.001	.008	3	1
SKCM	MIR489 →	+0.338	+7.816	<.001	.008	3	1
SKCM	MIR1302-4 →	+0.208	+7.816	<.001	.008	3	1
SKCM	RNU6-1135P →	+0.283	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

SNX3P1X by ATP5IF1 expression — UCEC

Explore this box plot interactively →