ATP5F1EP2

Across TCGA patient cohorts, ATP5F1EP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,085 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ATP5F1EP2-associated GO terms across cancer lineages are Iron-sulfur cluster assembly, DNA protection, and [4Fe-4S] cluster assembly. Each is linked with ATP5F1EP2 in more than 23 cancer types. Because this analysis shows association rather than direction, both ATP5F1EP2-to-partner and partner-to-ATP5F1EP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Iron-sulfur cluster assembly grouped by ATP5F1EP2-low versus ATP5F1EP2-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5F1EP2→partner) and Y-score (partner→ATP5F1EP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Iron-sulfur cluster assembly →	+0.069	+1.213	<.001	<.001	3	24
UCS	DNA protection →	+0.088	+0.520	<.001	.001	3	23
DLBC	[4Fe-4S] cluster assembly →	+0.106	+0.985	<.001	<.001	3	21
DLBC	Establishment of mitotic sister chromatid cohesion →	-0.092	-0.916	<.001	<.001	3	21
DLBC	Peptidyl-serine autophosphorylation →	-0.081	-0.705	<.001	<.001	3	21
DLBC	[2Fe-2S] cluster assembly →	+0.071	+0.948	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,085 associations by consensus.

Iron-sulfur cluster assembly by ATP5F1EP2 expression — DLBC

Explore this box plot interactively →