ATP5F1EP2

Across TCGA patient cohorts, ATP5F1EP2 mutation is significantly associated with the RNA expression of many other genes, with 50 significant associations in total. COAD shows the largest number of these associations.

The most reproducible ATP5F1EP2-associated genes across cancer lineages are RN7SKP143, IGLCOR22-2, and OSBPL9P3. Each is linked with ATP5F1EP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP5F1EP2-to-partner and partner-to-ATP5F1EP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP143 grouped by ATP5F1EP2-low versus ATP5F1EP2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5F1EP2→partner) and Y-score (partner→ATP5F1EP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SKP143 →	+0.096	+5.412	<.001	.001	3	2
LIHC	IGLCOR22-2 →	+0.255	+5.355	<.001	.005	3	1
LIHC	OSBPL9P3 →	+0.092	+7.169	<.001	<.001	3	1
LIHC	JRKL-AS1 →	+0.101	+5.758	.007	.003	3	1
LIHC	MIR4323 →	+0.522	+6.676	<.001	<.001	3	1
LIHC	LRRC10 →	+0.014	+5.033	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

RN7SKP143 by ATP5F1EP2 expression — COAD

Explore this box plot interactively →