ATP5F1AP7

Across TCGA pan-cancer cohorts, ATP5F1AP7 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated ATP5F1AP7 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ATP5F1AP7 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ATP5F1AP7 expression acts as an unfavorable survival marker, although some lineages such as SKCM and LGG show a favorable association.

HNSC, SKCM, and MESO are the cancer types where ATP5F1AP7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	IV	0.141	0.659	<.001	66	view →
SKCM	OS	Tertile	III,IV	0.901	0.664	.002	57	view →
MESO	OS	Tertile	III,IV	0.318	0.601	.018	45	view →
THYM	DFS	Tertile	II,III,IV	0.120	0.760	.004	36	view →
UCS	OS	Tertile	III,IV	0.340	0.628	.019	18	view →
BLCA	OS	Tertile	All	0.456	0.696	.049	18	view →
LUSC	OS	Tertile	III,IV	0.054	0.768	<.001	18	view →
LGG	OS	Tertile	All	1.000	0.888	.028	9	view →
OV	OS	Median	III,IV	0.871	0.804	.037	4	view →
KIRP	DFS	Tertile	All	1.000	0.847	.037	3	view →
KIRC	DFS	Tertile	All	0.908	0.794	.049	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

ATP5F1AP7–HNSC (OS)

Open the HNSC breakdown →