ATP4A

Across TCGA patient cohorts, ATP4A protein abundance is significantly associated with the RNA expression of many other genes, with 16,400 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATP4A-associated genes across cancer lineages are PRX, TFAP2E, and ERCC1. Each is linked with ATP4A in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP4A-to-partner and partner-to-ATP4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP4A versus PRX in OV, with a Pearson correlation of -0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP4A→partner) and Y-score (partner→ATP4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PRX →	-0.690	-1.664	.009	.003	3	1
OV	TFAP2E →	-0.867	-1.664	.003	.003	3	1
OV	ERCC1 →	-0.837	-1.665	.001	.003	3	1
OV	BIVM →	-1.085	-1.664	.009	.003	3	1
OV	MYC →	+0.752	+1.665	.003	.003	3	1
OV	IFNGR2 →	+0.536	+1.873	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,400 associations by consensus.

ATP4A vs PRX — OV

Explore this scatter interactively →