ATP4A

Across TCGA cell cohorts, ATP4A RNA expression is significantly associated with the go_rna of many other GO terms, with 995 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ATP4A-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Positive regulation of monoatomic ion transport, and RNA catabolic process. Each is linked with ATP4A in more than 7 cancer types. Because this analysis shows association rather than direction, both ATP4A-to-partner and partner-to-ATP4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by ATP4A-low versus ATP4A-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP4A→partner) and Y-score (partner→ATP4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Epigenetic regulation of gene expression →	+0.049	+0.107	<.001	.002	3	7
SOFT_TISSUE	Positive regulation of monoatomic ion transport →	-0.083	-0.067	<.001	.003	3	6
OVARY	RNA catabolic process →	+0.034	+0.087	<.001	.001	3	6
LUNG_NSCLC_LUAD	Regulation of telomerase RNA localization to Cajal body →	+0.033	+0.047	.006	.001	3	6
STOMACH	Positive regulation of translation →	+0.057	+0.055	.003	.002	1	8
OVARY	Nucleic acid catabolic process →	+0.032	+0.087	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 995 associations by consensus.

Epigenetic regulation of gene expression by ATP4A expression — OVARY

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