ATP2B4

Across TCGA cell cohorts, ATP2B4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,706 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ATP2B4-associated GO terms across cancer lineages are Urinary bladder smooth muscle contraction, Urinary tract smooth muscle contraction, and Negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway. Each is linked with ATP2B4 in more than 19 cancer types. Because this analysis shows association rather than direction, both ATP2B4-to-partner and partner-to-ATP2B4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Urinary bladder smooth muscle contraction grouped by ATP2B4-low versus ATP2B4-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2B4→partner) and Y-score (partner→ATP2B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Urinary bladder smooth muscle contraction →	+1.600	+2.466	<.001	<.001	3	20
LIVER	Urinary tract smooth muscle contraction →	+1.600	+2.466	<.001	<.001	3	20
LIVER	Negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway →	+0.220	+2.541	<.001	<.001	3	19
BREAST	Negative regulation of amino acid biosynthetic process →	+0.441	+1.961	<.001	<.001	3	19
BREAST	Negative regulation of amino acid metabolic process →	+0.441	+1.961	<.001	<.001	3	19
BONE	Response to hydrostatic pressure →	+0.258	+2.146	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,706 associations by consensus.

Urinary bladder smooth muscle contraction by ATP2B4 expression — LIVER

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