ATP2B4

Across TCGA cell cohorts, ATP2B4 mutation is significantly associated with the RNA expression of many other genes, with 659 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP2B4-associated genes across cancer lineages are UCK1, FBXL2, and PKDREJ. Each is linked with ATP2B4 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP2B4-to-partner and partner-to-ATP2B4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UCK1 grouped by ATP2B4-low versus ATP2B4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2B4→partner) and Y-score (partner→ATP2B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	UCK1 →	+0.595	+3.199	.007	.007	3	2
BLOOD_Leukemia	FBXL2 →	+0.584	+3.199	<.001	.007	3	2
LARGE_INTESTINE	PKDREJ →	+0.273	+3.160	<.001	.006	3	2
LARGE_INTESTINE	NEIL2 →	+0.694	+3.321	.003	.003	3	2
LARGE_INTESTINE	EML5 →	+0.896	+2.628	<.001	.002	3	2
LARGE_INTESTINE	ZNF219 →	+0.930	+3.169	.003	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 659 associations by consensus.

UCK1 by ATP2B4 expression — BLOOD_Leukemia

Explore this box plot interactively →