ATP2B2-IT2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ATP2B2-IT2 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated ATP2B2-IT2 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher ATP2B2-IT2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ATP2B2-IT2 expression acts as an unfavorable survival marker.

KICH, COAD, and UVM are the cancer types where ATP2B2-IT2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KICHDFSTertileII,III,IV0.3770.887.01363view →
COADDFSTertileAll0.1170.560.00439view →
UVMDFSTertileAll0.1410.745.01136view →
SKCMOSTertileII,III,IV0.2400.843<.00118view →
CESCOSTertileII,III,IV0.2270.759.02918view →
LGGOSTertileAll0.6570.817.02118view →
STADDFSTertileIV0.0830.379.0019view →
SARCDFSTertileAll0.2300.603.0049view →
Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

Exploration