ATP2B1

Across TCGA patient cohorts, ATP2B1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,470 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATP2B1-associated genes across cancer lineages are ATP2B1-AS1, MICAL1, and KRT15. Each is linked with ATP2B1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ATP2B1-to-partner and partner-to-ATP2B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP2B1 versus ATP2B1-AS1 in LSCC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2B1→partner) and Y-score (partner→ATP2B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ATP2B1-AS1 →	+0.506	+0.668	<.001	<.001	3	5
OV	MICAL1 →	-0.520	-0.226	.007	.008	3	4
LSCC	KRT15 →	+1.992	+0.467	<.001	<.001	3	4
COAD	TMEM255B →	-0.521	-0.200	<.001	<.001	3	4
CCRCC	AQP1 →	-1.136	-0.242	<.001	<.001	3	4
UCEC	ICAM2 →	-0.694	-0.560	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,470 associations by consensus.

ATP2B1 vs ATP2B1-AS1 — LSCC

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