ATP2B1

Across TCGA patient cohorts, ATP2B1 mutation is significantly associated with the total protein of many other genes, with 71 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP2B1-associated genes across cancer lineages are ATM, Di-Ras3, and AR. Each is linked with ATP2B1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP2B1-to-partner and partner-to-ATP2B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by ATP2B1-low versus ATP2B1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2B1→partner) and Y-score (partner→ATP2B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.398	-2.571	.001	<.001	3	3
UCEC	Di-Ras3 →	-0.140	-1.369	<.001	.003	3	3
SKCM	AR →	-0.151	-3.000	.049	.035	3	2
UCEC	FoxM1 →	+0.164	+1.722	.021	<.001	3	2
UCEC	GATA6 →	-0.099	-1.047	.025	.029	3	2
COAD	INPP4B →	-0.403	-3.000	.016	.035	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 71 associations by consensus.

ATM by ATP2B1 expression — UCEC

Explore this box plot interactively →