ATP2B1

Across TCGA cell cohorts, ATP2B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,240 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ATP2B1-associated GO terms across cancer lineages are Regulation of vascular associated smooth muscle contraction, Calcium ion export across plasma membrane, and Cold acclimation. Each is linked with ATP2B1 in more than 15 cancer types. Because this analysis shows association rather than direction, both ATP2B1-to-partner and partner-to-ATP2B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of vascular associated smooth muscle contraction grouped by ATP2B1-low versus ATP2B1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2B1→partner) and Y-score (partner→ATP2B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of vascular associated smooth muscle contraction →	+0.165	+1.270	<.001	<.001	2	16
UPPER_AERODIGESTIVE_TRACT	Calcium ion export across plasma membrane →	+1.333	+1.511	<.001	<.001	3	12
STOMACH	Cold acclimation →	+0.152	+0.740	<.001	<.001	3	12
SKIN	Phosphatidylinositol metabolic process →	+0.045	+1.124	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Nucleic acid transport →	+0.098	+1.211	.002	.004	3	11
UPPER_AERODIGESTIVE_TRACT	RNA transport →	+0.098	+1.211	.002	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,240 associations by consensus.

Regulation of vascular associated smooth muscle contraction by ATP2B1 expression — BONE

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