Across TCGA patient cohorts, ATP2A1 mutation is significantly associated with the RNA expression of many other genes, with 2,788 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP2A1-associated genes across cancer lineages are RPSAP9, RNU6-1133P, and SKA1. Each is linked with ATP2A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP2A1-to-partner and partner-to-ATP2A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2A1→partner) and Y-score (partner→ATP2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPSAP9 →	+0.354	+3.220	<.001	.009	3	3
HNSC	RNU6-1133P →	+0.236	+4.240	.001	.001	3	3
SKCM	SKA1 →	+0.696	+3.459	.002	.005	3	3
UCEC	POC1A →	+0.380	+1.793	.007	.001	3	3
UCEC	SFXN1 →	+0.358	+1.761	<.001	<.001	3	3
UCEC	SAAL1 →	+0.364	+1.601	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,788 associations by consensus.

Exploration

ATP2A1 survival (RNA) · tumor vs normal (RNA) · all ATP2A1 data types