ATP2A1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP2A1 mutation is significantly associated with the total protein of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP2A1-associated genes across cancer lineages are FoxM1, GAPDH, and INPP4B. Each is linked with ATP2A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP2A1-to-partner and partner-to-ATP2A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2A1→partner) and Y-score (partner→ATP2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADFoxM1 →+0.316+3.000.020.03632
UCECGAPDH →+0.439+2.392.003<.00132
COADINPP4B →-0.391-3.000.026.03432
UCECMEK1 →+0.456+1.830<.001<.00132
UCECNotch1 →+0.107+1.232.006.02132
UCECp27_pT198 →+0.077+0.947.010.04732
Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

Exploration