Across TCGA cell cohorts, ATP2A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,541 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ATP2A1-associated GO terms across cancer lineages are Regulation of twitch skeletal muscle contraction, Relaxation of skeletal muscle, and Regulation of ATPase-coupled calcium transmembrane transporter activity. Each is linked with ATP2A1 in more than 18 cancer types. Because this analysis shows association rather than direction, both ATP2A1-to-partner and partner-to-ATP2A1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2A1→partner) and Y-score (partner→ATP2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of twitch skeletal muscle contraction →	+1.437	+1.767	<.001	<.001	3	19
LUNG_NSCLC_LUSC	Relaxation of skeletal muscle →	+1.402	+1.948	<.001	<.001	3	17
LIVER	Regulation of ATPase-coupled calcium transmembrane transporter activity →	-0.369	-1.763	<.001	<.001	3	17
KIDNEY	Regulation of calcium ion import into sarcoplasmic reticulum →	+1.466	+2.154	<.001	<.001	3	16
PANCREAS	Positive regulation of striated muscle contraction →	-0.266	-1.250	<.001	<.001	3	13
LUNG_SCLC	Subtelomeric heterochromatin formation →	+0.135	+1.120	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,541 associations by consensus.

Exploration

ATP2A1 survival (RNA) · tumor vs normal (RNA) · all ATP2A1 data types