Across TCGA cell cohorts, ATP2A1 mutation is significantly associated with the mutation status of many other genes, with 7,118 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP2A1-associated genes across cancer lineages are SETD1A, SCAF4, and PRRC2A. Each is linked with ATP2A1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ATP2A1-to-partner and partner-to-ATP2A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2A1→partner) and Y-score (partner→ATP2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SETD1A →	+3.384	+4.169	<.001	<.001	1	7
STOMACH	SCAF4 →	+4.000	+4.700	<.001	<.001	1	7
BLOOD_Lymphoma	PRRC2A →	+3.969	+4.523	<.001	<.001	1	6
LUNG_NSCLC_LUAD	USP19 →	+4.063	+3.584	.003	.003	1	6
LARGE_INTESTINE	GREB1 →	+2.655	+2.413	<.001	<.001	1	6
LARGE_INTESTINE	DNAH5 →	+0.922	+2.035	.009	.009	1	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,118 associations by consensus.

Exploration

ATP2A1 survival (RNA) · tumor vs normal (RNA) · all ATP2A1 data types