ATP1B3

Across TCGA pan-cancer cohorts, ATP1B3 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ATP1B3 data layer compared with 28 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ATP1B3 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ATP1B3 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LSCC, PDAC, and HNSC are the cancer types where ATP1B3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	III,IV	0.909	0.424	.010	6	view →
PDAC	OS	Median	All	0.817	0.905	.018	3	view →
HNSC	DFS	Quartile	IV	0.650	0.812	.030	1	view →
GBM	DFS	Median	All	0.672	0.824	.034	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ATP1B3–LSCC (DFS)

Open the LSCC breakdown →