ATP1B3

Across TCGA patient cohorts, ATP1B3 mutation is significantly associated with the RNA expression of many other genes, with 484 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP1B3-associated genes across cancer lineages are MIR4307, RNU6-1292P, and MIR519E. Each is linked with ATP1B3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP1B3-to-partner and partner-to-ATP1B3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4307 grouped by ATP1B3-low versus ATP1B3-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP1B3→partner) and Y-score (partner→ATP1B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR4307 →	+0.245	+7.731	<.001	.009	3	3
CESC	RNU6-1292P →	+0.466	+6.837	<.001	<.001	3	2
BRCA	MIR519E →	+0.462	+8.055	<.001	.007	3	2
SKCM	RNA5SP387 →	+0.463	+6.080	<.001	.002	3	2
UCEC	IGHD6-13 →	+0.735	+2.759	<.001	.005	3	2
HNSC	LINC02536 →	+0.066	+5.368	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 484 associations by consensus.

MIR4307 by ATP1B3 expression — BRCA

Explore this box plot interactively →