ATP1B3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ATP1B3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,196 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ATP1B3-associated GO terms across cancer lineages are Positive regulation of mRNA processing, Membrane repolarization, and Negative regulation of mitotic cell cycle phase transition. Each is linked with ATP1B3 in more than 8 cancer types. Because this analysis shows association rather than direction, both ATP1B3-to-partner and partner-to-ATP1B3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA processing grouped by ATP1B3-low versus ATP1B3-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP1B3→partner) and Y-score (partner→ATP1B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaPositive regulation of mRNA processing →+0.123+1.271<.001<.00139
BREASTMembrane repolarization →+0.215+0.895<.001.00138
BREASTNegative regulation of mitotic cell cycle phase transition →+0.071+1.215<.001<.00137
BREASTProtein localization to nuclear inner membrane →+0.095+0.943<.001<.00128
BLOOD_LeukemiaCellular response to cisplatin →+0.125+0.591<.001<.00137
BLOOD_LeukemiaDNA replication checkpoint signaling →+0.095+0.517<.001.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,196 associations by consensus.

Positive regulation of mRNA processing by ATP1B3 expression — BLOOD_Myeloma

Box plot of Positive regulation of mRNA processing in ATP1B3-low vs ATP1B3-high samples in BLOOD_Myeloma.

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Exploration