ATP1B3-AS1

Across TCGA pan-cancer cohorts, ATP1B3-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated ATP1B3-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ATP1B3-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ATP1B3-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

HNSC, UVM, and KIRC are the cancer types where ATP1B3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.706	0.516	<.001	111	view →
UVM	DFS	Quartile	III,IV	0.195	0.788	.002	53	view →
KIRC	DFS	Quartile	All	0.516	0.695	.003	42	view →
MESO	OS	Median	All	0.274	0.481	.002	30	view →
ACC	DFS	Tertile	All	0.430	0.872	.001	29	view →
BLCA	DFS	Quartile	IV	0.165	0.505	.015	27	view →
SKCM	OS	Tertile	III,IV	0.836	0.723	.015	21	view →
LGG	DFS	Median	All	0.789	0.871	.005	19	view →
LIHC	DFS	Tertile	All	0.451	0.641	<.001	18	view →
PRAD	DFS	Tertile	All	0.706	0.834	.007	18	view →
THCA	OS	Median	II,III,IV	0.792	0.940	.014	17	view →
THYM	OS	Tertile	All	1.000	0.715	.009	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

ATP1B3-AS1–HNSC (DFS)

Open the HNSC breakdown →