ATP1A4

Across TCGA cell cohorts, ATP1A4 mutation is significantly associated with the RNA expression of many other genes, with 410 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP1A4-associated genes across cancer lineages are MORC1, OR4M2, and MRPL42. Each is linked with ATP1A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP1A4-to-partner and partner-to-ATP1A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MORC1 grouped by ATP1A4-low versus ATP1A4-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP1A4→partner) and Y-score (partner→ATP1A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	MORC1 →	+0.079	+3.635	<.001	.007	3	2
SOFT_TISSUE	OR4M2 →	+0.098	+4.515	<.001	<.001	3	2
LARGE_INTESTINE	MRPL42 →	+0.670	+3.212	<.001	.006	3	2
LARGE_INTESTINE	ADAM7 →	+0.003	+2.760	<.001	.003	3	2
SOFT_TISSUE	TSPO2 →	+0.053	+3.865	.004	.006	3	1
SOFT_TISSUE	TM4SF5 →	+0.048	+4.459	.008	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 410 associations by consensus.

MORC1 by ATP1A4 expression — SOFT_TISSUE

Explore this box plot interactively →